Pittsburgh Steelers
| Week # | Date | Opponent | Results | Record | Streak | |
|---|---|---|---|---|---|---|
| 1 | Sunday, Sep. 7 |
@
NYJ
|
W 34-32 | 1-0-0 | Won 1 | Boxscore |
| 2 | Sunday, Sep. 14 |
vs
Sea
|
L 31-17 | 1-1-0 | Lost 1 | Boxscore |
| 3 | Sunday, Sep. 21 |
@
NE
|
W 21-14 | 2-1-0 | Won 1 | Boxscore |
| 4 | Sunday, Sep. 28 |
vs
Min
|
W 24-21 | 3-1-0 | Won 2 | Boxscore |
| 6 | Sunday, Oct. 12 |
vs
Cle
|
W 23-9 | 4-1-0 | Won 3 | Boxscore |
| 7 | Thursday, Oct. 16 |
@
Cin
|
L 33-31 | 4-2-0 | Lost 1 | Boxscore |
| 8 | Sunday, Oct. 26 |
vs
GB
|
L 35-25 | 4-3-1 | Lost 2 | Boxscore |
| 9 | Sunday, Nov. 2 |
vs
Ind
|
W 27-20 | 5-3-0 | Won 1 | Boxscore |
VS.
Pittsburgh Steelers
STAT RANK
November 1, 2025
| Lew Nichols III (RB) | Activated from the practice squad by the Pittsburgh Steelers. |
| Trey Sermon (RB) | Activated from the practice squad by the Pittsburgh Steelers. |
October 31, 2025
| DeShon Elliott (S) | Knee injury, injured reserve. |
October 30, 2025
| Kyle Dugger (S) | Acquired from the New England Patriots |
October 29, 2025
| Jack Driscoll (OG/OT) | Signed by the Pittsburgh Steelers to the practice squad. |
| John Rhys Plumlee (WR) | Signed by the Pittsburgh Steelers to the practice squad. |
October 28, 2025
| Darrick Forrest (S) | Signed by the Pittsburgh Steelers to the practice squad. |
| Domenique Davis (NT/DT) | Released by the Pittsburgh Steelers. |
| Jacoby Windmon (LB) | Released by the Pittsburgh Steelers from the practice squad. |
| Raheem Blackshear (RB) | Released by the Pittsburgh Steelers from the practice squad. |