4:39 PM - Christian McCaffrey (SF) rushed 28 times for 106 yards and a touchdown while catching five of six targets for 67 yards and a touchdown in Sunday's 34-24 win over the Giants.

5:13 PM - Christian McCaffrey (SF) rushed eight times for 25 yards and brought in three of six targets for 43 yards in the 49ers' 26-15 loss to the Texans on Sunday.

7:49 PM - Christian McCaffrey (SF) took 17 carries for 54 yards and a touchdown while hauling in seven of eight targets for 57 yards in Sunday's 30-19 loss to the Buccaneers.

7:48 PM - Christian McCaffrey (SF) rushed 17 times for 52 yards while corralling 10 of 15 targets for 88 yards in Sunday's 16-15 victory over the Cardinals.

5:06 PM - Christian McCaffrey (SF) carried the ball 13 times for 55 yards and caught six of seven targets for 52 yards and a touchdown in Sunday's 26-21 win over the Saints.

7:40 PM - Christian McCaffrey (SF) (calf) handled 22 carries for 69 yards and nine receptions for 73 yards on 10 targets in Sunday's 17-13 win over the Seahawks.

2:35 PM - Christian McCaffrey (SF) (calf) is active for Sunday's game against the Seahawks.

11:13 AM - Christian McCaffrey (SF) (calf) is expected to play in Sunday's season opener against the Seahawks, Adam Schefter of ESPN reports.

9:47 AM - Christian McCaffrey (SF) (calf) remains listed as questionable for Sunday's game in Seattle, though he's still "trending" toward playing after he was a "big participant" in the 49ers' team walk-through Saturday, Ian Rapoport of NFL Network reports.

3:55 PM - Christian McCaffrey (SF) (calf), who is officially listed as questionable for Sunday's road game against the Seahawks, is expected to suit up unless he suffers any setbacks, Ian Rapoport of NFL Network reports.

5:40 PM - Christian McCaffrey (SF) (calf), who is listed as questionable for Sunday's game at Seattle, said Friday that he "feels great" and is preparing to suit up Week 1, David Lombardi of SFStandard.com reports.

5:06 PM - Christian McCaffrey (SF) Kyle Shanahan said Friday that McCaffrey (calf) is listed as questionable for Sunday's game in Seattle, Nick Wagoner of ESPN.com reports.

3:42 PM - Christian McCaffrey (SF) (calf) is warming up in uniform at the start of Friday's practice, Nick Wagoner of ESPN.com reports.

7:58 PM - Christian McCaffrey (SF) was limited at Thursday's practice due to a calf injury, Cam Inman of The San Jose Mercury News reports.

8:03 PM - Christian McCaffrey (SF) isn't warming up ahead of Saturday's preseason contest versus the Chargers, Matt Barrows of The Athletic reports.

3:52 PM - Christian McCaffrey (SF) will not join Brock Purdy and the majority of San Francisco's starters in suiting up for Saturday's preseason game against the Raiders, David Lombardi of SFStandard.com reports.

6:20 PM - Christian McCaffrey (SF) is not in line to play in Saturday's preseason opener against the Broncos, Eric Branch of the San Francisco Chronicle and David Lombardi of SFStandard.com report.

5:14 PM - Christian McCaffrey (SF) Kyle Shanahan said Tuesday that McCaffrey is "here and healthy" for the start of 49ers training camp, but the running back's workload will be managed in advance of the regular season, Nick Wagoner of ESPN.com reports.

10:03 AM - Christian McCaffrey (SF) is participating in the offseason program without any restrictions, ESPN.com's Nick Wagoner reports.

10:55 AM - Christian McCaffrey (SF) Francisco coach Kyle Shanahan said last week that McCaffrey (knee) is healthy and doing well, Matt Maiocco of NBC Sports Bay Area reports.

4:00 PM - Christian McCaffrey (SF) (knee) said Monday he's "definitely close" to 100 percent healthy and could have played had the 49ers qualified for the playoffs, Nick Wagoner of ESPN.com reports.

5:17 PM - Christian McCaffrey (SF) 49ers placed McCaffrey (knee) on injured reserve Tuesday.

4:46 PM - Christian McCaffrey (SF) 49ers placed McCaffrey (knee) on injured reserve Monday, Ian Rapoport of NFL Network reports.

5:18 PM - Christian McCaffrey (SF) (Achilles) doesn't have an injury designation for Sunday's game against Seattle, Cam Inman of The San Jose Mercury News reports.

4:49 PM - Christian McCaffrey (SF) Kyle Shanahan said McCaffrey (Achilles) will be a limited practice participant Wednesday, Nick Wagoner of ESPN.com reports.

4:26 PM - Christian McCaffrey (SF) (Achilles) rushed 13 times for 39 yards and caught six of seven targets for 68 yards in Sunday's 23-20 win over Tampa Bay.

11:34 AM - Christian McCaffrey (SF) (Achilles) is listed as active Sunday at Tampa Bay, Lindsey Pallares of the 49ers' official site reports.

9:34 AM - Christian McCaffrey (SF) (Achilles) remains listed as questionable for Sunday's game against the Buccaneers, but he's on track to play and expressed confidence that he's take on his usual workload in his season debut, Mike Garafolo of NFL Network reports.

4:07 PM - Christian McCaffrey (SF) (Achilles) was activated off injured reserve Saturday, Adam Schefter of ESPN reports.

4:45 PM - Christian McCaffrey (SF) (Achilles) is listed as questionable for Sunday's game at Tampa Bay, with coach Kyle Shanahan saying Friday that the running back will play, Eric Branch of the San Francisco Chronicle reports.

6:58 PM - Christian McCaffrey (SF) Kyle Shanahan said Thursday that he expects McCaffrey (Achilles) to make his season debut Sunday at Tampa Bay, David Lombardi of The San Francisco Standard reports.

6:35 PM - Christian McCaffrey (SF) (Achilles) was limited at Thursday's practice, Nick Wagoner of ESPN.com reports.

4:09 PM - Christian McCaffrey (SF) Kyle Shanahan said McCaffrey will be limited at Wednesday's practice, but the running back has exhibited "no pain" with his Achilles, Adam Schefter of ESPN reports.

2:16 PM - Christian McCaffrey (SF) 49ers designated McCaffrey (Achilles) to return from injured reserve Monday.

9:50 AM - Christian McCaffrey (SF) Francisco head coach Kyle Shanahan said Monday that McCaffrey (Achilles) will remain in the Bay Area during the 49ers' Week 9 bye to take part in "simulated practice stuff," Nick Wagoner of ESPN.com reports. "It depends how this week goes," Shanahan said, when asked if McCaffrey will be available to make his season debut Week 10 at Tampa Bay. "He's had no setbacks, so it looks like we're on track, but he's going to hit it hard this week while we're gone...as long as it all goes good, hopefully we'll get him back in practice next week."

12:04 PM - Christian McCaffrey (SF) (Achilles) is on track to participate in a "bonus" practice that the 49ers have scheduled during their Week 9 bye, Ian Rapoport of NFL Network reports.

7:08 PM - Christian McCaffrey (SF) Kyle Shanahan said Monday that McCaffrey (Achilles) is unlikely to practice this week, but the 49ers are hopeful the running back will be able to return after their Week 9 bye on Sunday, Nov. 10 at Tampa Bay, Nick Wagoner of ESPN.com reports.

3:11 PM - Christian McCaffrey (SF) Kyle Shanahan said Friday that McCaffrey (Achilles) won't return to practice next week, Nick Wagoner of ESPN.com reports.

7:08 PM - Christian McCaffrey (SF) Kyle Shanahan said Monday that McCaffrey is tending to tendinitis in both of his Achilles, Nick Wagoner of ESPN.com reports. "I think it started in one, and you overcompensate, it went to the other," Shanahan added. "Mainly one of them has just been bothering him, but he's had it in both."

9:58 AM - Christian McCaffrey (SF) a chance McCaffrey (Achilles) could run on hard ground this coming week, Ian Rapoport of NFL Network reports.

5:34 PM - Christian McCaffrey (SF) Kyle Shanahan said Friday that McCaffrey (Achilles) may "start hitting the rehab here harder on Monday," Nick Wagoner of ESPN.com reports.

7:34 PM - Christian McCaffrey (SF) Kyle Shanahan said Thursday on 104.5 KNBR that the 49ers will "probably turn it up here in the next couple of weeks" with McCaffrey (calf/Achilles). "We'll start testing it out here sooner rather than later," Shanahan added.

6:53 PM - Christian McCaffrey (SF) Kyle Shanahan said Monday that McCaffrey is in Germany to visit with a specialist for his Achilles tendinitis, Nick Wagoner of ESPN.com reports.

9:36 AM - Christian McCaffrey (SF) (calf), who was placed on injured reserve Saturday, is "likely to be out six weeks or potentially more" while he recovers from Achilles tendinitis, Ian Rapoport of NFL Network reports.

1:26 PM - Christian McCaffrey (SF) Schefter of ESPN reports that McCaffrey (Achilles/calf) will be placed on injured reserve Saturday.

7:28 PM - Christian McCaffrey (SF) 49ers may place McCaffrey (calf/Achilles) on injured reserve Saturday, Ian Rapoport of NFL Network reports.

5:06 PM - Christian McCaffrey (SF) has been ruled out for Sunday's game against the Vikings. The 49ers are considering playing him on injured reserve, which would sideline him this week plus three more games, Tom Pelissero of NFL Network reports.

3:53 PM - Christian McCaffrey (SF) (Achilles) is not present at the portion of Friday's practice open to the media, Nick Wagoner of ESPN.com reports.

11:18 AM - Christian McCaffrey (SF) GM John Lynch said Friday morning that he doesn't know if McCaffrey (Achilles) will play Sunday at the Vikings, Cam Inman of The San Jose Mercury News reports.

6:58 PM - Christian McCaffrey (SF) (calf/Achilles) remained limited at Thursday's practice, Adam Caplan of SiriusXM NFL Radio reports.

4:20 PM - Christian McCaffrey (SF) (Achilles/calf) is in uniform and expected to participate in Thursday's practice, Cam Inman of The San Jose Mercury News reports.

3:54 PM - Christian McCaffrey (SF) Kyle Shanahan said McCaffrey (calf/Achilles) will be a limited practice participant Wednesday, Cam Inman of The San Jose Mercury News reports.

9:32 AM - Christian McCaffrey (SF) (Achilles/calf) appears to be a "long shot" to play Sunday against the Vikings, sources tell Ian Rapoport of NFL Network reports.

2:27 PM - Christian McCaffrey (SF) Francisco head coach Kyle Shanahan labeled McCaffrey (calf/Achilles) as day-to-day heading into Sunday's game against the Vikings, Nick Wagoner of ESPN.com reports.

6:56 PM - Christian McCaffrey (SF) (calf/Achilles) is listed as inactive Monday against the Jets, Lindsey Pallares of the 49ers' official site reports.

6:53 PM - Christian McCaffrey (SF) (calf/Achilles) is in line to be inactive Monday against the Jets, Mike Garafolo of NFL Network reports.

10:18 AM - Christian McCaffrey (SF) (calf/Achilles) remains listed as questionable, but he expects to play Monday against the Jets and handle something close to a normal workload, Ian Rapoport of NFL Network reports.

4:57 PM - Christian McCaffrey (SF) (calf/Achilles) is listed as questionable for Monday's game against the Jets, Nick Wagoner of ESPN.com reports.

6:57 PM - Christian McCaffrey (SF) (calf/Achilles) said Friday that he has no doubt he'll play Monday against the Jets, Nick Wagoner of ESPN.com reports.

6:40 PM - Christian McCaffrey (SF) (calf) was a limited practice participant Friday, Nick Wagoner of ESPN.com reports.

4:46 PM - Christian McCaffrey (SF) (calf/Achilles) is practicing Friday and appears to be "moving at full speed with no issue," according to Nick Wagoner of ESPN.com.

11:42 AM - Christian McCaffrey (SF) John Lynch said Friday morning that he expects McCaffrey (calf/Achilles) to play Monday against the Jets, Cam Inman of The San Jose Mercury News reports.

4:05 PM - Christian McCaffrey (SF) Kyle Shanahan said McCaffrey (calf/Achilles) will be a limited participant at Thursday's practice, Eric Branch of the San Francisco Chronicle reports.

2:24 PM - Christian McCaffrey (SF) (calf) is in uniform for the portion of Tuesday's practice open to the media, Matt Barrows of The Athletic reports.

9:15 AM - Christian McCaffrey (SF) (calf) is expected to return to practice Tuesday, Adam Schefter of ESPN reports.

4:43 PM - Christian McCaffrey (SF) (calf) increased his activity level on the side field at practice Thursday and seems to be getting closer to a return, Nick Wagoner of ESPN.com reports.

1:31 PM - Christian McCaffrey (SF) 49ers signed McCaffrey to a two-year, $38 million contract extension Tuesday, Adam Schefter of ESPN reports.

6:48 PM - Christian McCaffrey (SF) (calf) will not practice this week, but head coach Kyle Shanahan expects him back next week leading up to the 49ers' Round 2 game, Nick Wagoner of ESPN.com reports.

5:36 PM - Christian McCaffrey (SF) Kyle Shanahan relayed Monday that McCaffrey is dealing with a mild calf strain and won't play Sunday against the Rams, Nick Wagoner of ESPN.com and Cam Inman of The San Jose Mercury News report.

4:35 PM - Christian McCaffrey (SF) Kyle Shanahan relayed after Sunday's 27-10 win over the Commanders that McCaffrey may be dealing with a calf strain, Eric Branch of the San Francisco Chronicle reports.

3:20 PM - Christian McCaffrey (SF) exited Sunday's game against the Commanders with a right calf injury and is questionable to return.

11:22 AM - Christian McCaffrey (SF) (oblique) is trending toward being active Monday against the Vikings, Adam Schefter of ESPN reports.

4:39 PM - Christian McCaffrey (SF) (oblique) was working on the side with San Francisco's training staff during the open portion of practice Friday, Nick Wagoner of ESPN.com reports.

3:55 PM - Christian McCaffrey (SF) Kyle Shanahan said Thursday that McCaffrey (oblique) won't take part in the 49ers' first official practice of Week 7 prep, Nick Wagoner of ESPN.com reports.

5:21 PM - Christian McCaffrey (SF) (oblique/ribs) is undergoing an MRI on Monday, Matt Barrows of The Athletic reports.

5:47 PM - Christian McCaffrey (SF) Kyle Shanahan said after Sunday's 19-17 loss at Cleveland that McCaffrey suffered oblique and rib injuries during the contest, Nick Wagoner of ESPN.com reports.

2:58 PM - Christian McCaffrey (SF) (calf) returned to practice Friday, Matt Barrows of The Athletic reports.

6:09 PM - Christian McCaffrey (SF) (calf), who didn't practice Thursday, told Matt Maiocco of NBC Sports Bay Area that there's "zero" chance that he doesn't play in Sunday's NFC Championship Game in Philadelphia.

2:52 PM - Christian McCaffrey (SF) Kyle Shanahan said McCaffrey (calf) won't participate in Thursday's practice, Matt Maiocco of NBC Sports Bay Area reports.

2:53 PM - Christian McCaffrey (SF) (calf) is considered day-to-day, but coach Kyle Shanahan said Monday that he expects to play in Sunday's NFC Championship Game against the Eagles, David Lombardi of The Athletic reports.

10:01 AM - Christian McCaffrey (SF) noted after Sunday's 19-12 win over the Cowboys in the divisional round that the right calf issue that resulted in him ceding snaps to backup Elijah Mitchell late in the contest is "all good" and won't affect his availability for this weekend's NFC Championship Game matchup with the Eagles, Cam Inman of The San Jose Mercury News reports. "I was fighting but made it through, made it through great," said. "[The calf] is nothing bad."

11:25 PM - Christian McCaffrey (SF) rushed 10 times for 35 yards and a touchdown and caught six of eight targets for 22 yards in Sunday's 19-12 playoff win over the Cowboys.

8:42 PM - Christian McCaffrey (SF) rushed 15 times for 119 yards and caught both of his targets for 17 yards and a touchdown in Saturday's 41-23 playoff win over Seattle.

5:20 PM - Christian McCaffrey (SF) (knee) doesn't have a designation for Saturday's wild-card game against the Seahawks, Matt Barrows of The Athletic reports.

7:59 PM - Christian McCaffrey (SF) (knee) practiced in a limited fashion Wednesday.

6:58 PM - Christian McCaffrey (SF) (ankle/knee) was a limited participant at Tuesday's practice, Eric Branch of the San Francisco Chronicle reports.

5:12 PM - Christian McCaffrey (SF) (ankle/knee) has no injury designation for Sunday's game against the Cardinals, Matt Maiocco of NBC Sports Bay Area reports.

4:32 PM - Christian McCaffrey (SF) (ankle/knee) returned to practice Friday, Matt Barrows of The Athletic reports.

7:36 PM - Christian McCaffrey (SF) (ankle/knee) didn't practice Thursday, Matt Maiocco of NBC Sports Bay Area reports.

3:30 PM - Christian McCaffrey (SF) (ankle) won't take part in Wednesday's practice, David Lombardi of The Athletic reports.

6:50 PM - Christian McCaffrey (SF) is considered day-to-day with a mild ankle sprain, Cam Inman of The San Jose Mercury News reports.

8:54 PM - Christian McCaffrey (SF) rushed 19 times for 121 yards and a touchdown while adding six receptions on nine targets for 72 yards in Sunday's 34-31 overtime win over Las Vegas.

4:46 PM - Christian McCaffrey (SF) (knee) doesn't have an injury designation for Sunday's game against the Raiders, Jennifer Lee Chan of NBC Sports Bay Area reports.

7:08 PM - Christian McCaffrey (SF) (knee) was limited at Thursday's practice, Eric Branch of the San Francisco Chronicle reports.

3:08 PM - Christian McCaffrey (SF) (knee) will be a limited practice participant Wednesday, Jennifer Lee Chan of NBC Sports Bay Area reports.

9:19 PM - Christian McCaffrey (SF) rushed 15 times for 46 yards and a touchdown while chipping in two receptions for 12 yards in Saturday's 37-20 win over Washington.

5:11 PM - Christian McCaffrey (SF) (knee) doesn't have a designation for Saturday's contest against the Commanders, Nick Wagoner of ESPN.com reports.

7:05 PM - Christian McCaffrey (SF) (knee) practiced in a limited fashion Wednesday, Nick Wagoner of ESPN.com reports.

3:40 PM - Christian McCaffrey (SF) (knee) will be a limited practice participant Tuesday, Cam Inman of The San Jose Mercury News reports.

11:45 PM - Christian McCaffrey (SF) rushed 26 times for 108 yards and a touchdown while bringing in six of eight targets for 30 yards in the 49ers' 21-13 win over the Seahawks on Thursday night.